Journal article icon

Journal article

Osteoclast formation and activity in the pathogenesis of osteoporosis in rheumatoid arthritis.

Abstract:

OBJECTIVE: Rheumatoid arthritis (RA) is often complicated by generalized osteopenia due to increased bone resorption by osteoclasts. We analysed a number of cellular and humoral factors that influence osteoclast formation from circulating precursors in RA patients. METHODS: Monocytes isolated from RA patients and normal controls were cultured with macrophage colony-stimulating factor (M-CSF) and nuclear factor-kappaB ligand (RANKL), or with RANKL-expressing UMR106 cells and 1,25 dihydroxyvita...

Expand abstract
Publication status:
Published

Actions


Access Document


Authors


More by this author
Institution:
University of Oxford
Division:
MSD
Department:
NDORMS
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
NDORMS
Role:
Author
Journal:
Rheumatology (Oxford, England)
Volume:
41
Issue:
11
Pages:
1232-1239
Publication date:
2002-11-01
DOI:
EISSN:
1462-0332
ISSN:
1462-0324
Source identifiers:
103836

Terms of use


Views and Downloads






If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP