Journal article
B cell memory to a serogroup C meningococcal conjugate vaccine in childhood and response to booster: little association with serum IgG antibody.
- Abstract:
-
The maintenance of adequate serum Ab levels following immunization has been identified as the most important mechanism for individual long-term protection against rapidly invading encapsulated bacteria. The mechanisms for maintaining adequate serum Ab levels and the relationship between Ag-specific memory B cells and Ab at steady state are poorly understood. We measured the frequency of circulating serogroup C meningococcal (MenC)-specific memory B cells in 250 healthy 6- to 12-y-old children...
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- Publication status:
- Published
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- Publisher copy:
- 10.4049/jimmunol.1200451
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Authors
Bibliographic Details
- Journal:
- Journal of Immunology
- Volume:
- 189
- Issue:
- 5
- Pages:
- 2673-2681
- Publication date:
- 2012-09-01
- DOI:
- EISSN:
-
1550-6606
- ISSN:
-
0022-1767
- Source identifiers:
-
344202
Item Description
- Language:
- English
- Keywords:
- Pubs id:
-
pubs:344202
- UUID:
-
uuid:4147f1e2-f747-4a18-a818-92480cbb510a
- Local pid:
- pubs:344202
- Deposit date:
- 2012-12-19
Terms of use
- Copyright date:
- 2012
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