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Journal article

Typhoid fever and genetic polymorphisms at the natural resistance-associated macrophage protein 1.

Abstract:

Control of Salmonella enterica serovar Typhimurium (S. typhimurium) infection in the mouse model of typhoid fever is critically dependent on the natural resistance-associated macrophage protein 1 (Nramp1). In this study, we examined the role of genetic polymorphisms in the human homologue, NRAMP1, in resistance to typhoid fever in southern Vietnam. Patients with blood-culture-confirmed typhoid fever and healthy control subjects were genotyped for 6 polymorphic markers within and near NRAMP1 o...

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Publication status:
Published

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Publisher copy:
10.1086/319289

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Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Medicine, Tropical Medicine
Role:
Author
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Journal:
The Journal of infectious diseases
Volume:
183
Issue:
7
Pages:
1156-1160
Publication date:
2001-04-05
DOI:
EISSN:
1537-6613
ISSN:
0022-1899
URN:
uuid:41439ebc-034a-4ec6-a2b6-5b25c7108f22
Source identifiers:
31837
Local pid:
pubs:31837

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