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Thesis

Characterisation of neuroserpin protein expression throughout development and investigation of putative neuroprotective properties in rodent models of neonatal hypoxia ischaemia

Abstract:

Neonatal hypoxia ischaemia remains the most common cause of infant mortality globally, accounting for persistent motor and cognitive disorders in a substantial proportion of survivors. Currently, there is only one licensed treatment which aims to reduce brain damage and improve cognitive function: hypothermia. Increased understanding of the infant brain’s response to hypoxic ischaemic injury and novel treatment design are of utmost importance. This thesis characterises expression of neuron...

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Institution:
University of Oxford
Division:
MSD
Role:
Author

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Department:
Department of Physiology, Anatomy, and Genetics
Role:
Supervisor
Type of award:
DPhil
Level of award:
Doctoral
Awarding institution:
University of Oxford

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