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Metabolic consequences and predictability of ventricular fibrillation in hypoxia. A 31P- and 23Na-nuclear magnetic resonance study of the isolated rat heart.

Abstract:

BACKGROUND: Ventricular fibrillation has deleterious metabolic and functional consequences for the heart. This study had two purposes: first, to define the effects of ventricular fibrillation during hypoxia on energy metabolism and accumulation of intracellular Na+ and, second, to test whether the occurrence of ventricular fibrillation can be predicted from functional or metabolic parameters. METHODS AND RESULTS: Isolated isovolumic rat hearts were perfused with oxygenated Krebs-Henseleit buf...

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Publisher copy:
10.1161/01.cir.86.1.302

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Institution:
University of Oxford
Department:
Oxford, MSD, RDM, Cardiovascular Medicine, BHF Centre of Research Excellence
Role:
Author
Journal:
Circulation
Volume:
86
Issue:
1
Pages:
302-310
Publication date:
1992-07-05
DOI:
EISSN:
1524-4539
ISSN:
0009-7322
URN:
uuid:411019c3-29d0-4f59-983a-2e7c2f659be6
Source identifiers:
441427
Local pid:
pubs:441427

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