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Thesis

The histone deacetylase inhibitor panobinostat as a radiosensitiser in bladder cancer

Abstract:

Muscle invasive bladder cancer (MIBC) has a poor prognosis. Currently, therapy consists of radical radiotherapy or cystectomy with or without chemotherapy. The average age of patients with MIBC is high and older patients are less able to tolerate surgery or chemoradiation due to their impaired physical fitness and generally poor renal function. There is an urgent need to find new treatment regimes that are both tolerable and effective.

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Institution:
University of Oxford
Oxford college:
Wolfson College
Department:
Medical Sciences Division - Medical Oncology
Role:
Author

Contributors

Role:
Supervisor
Role:
Supervisor
Publication date:
2014
Type of award:
DPhil
Level of award:
Doctoral
Awarding institution:
Oxford University, UK
URN:
uuid:40f48d00-8d74-41db-8630-ceacf22f3e78
Local pid:
ora:9789

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