Identification of anticoagulant activities in salivary gland extracts of four horsefly species (Diptera, tabanidae).

Kazimírová, M; Sulanová, M; Kozánek, M; Takác, P; Labuda, M; Nuttall, PA

Abstract:

Anticoagulant activities against the extrinsic and intrinsic coagulation pathways were identified in salivary gland extracts (SGE) prepared from four tabanids (Hybomitra muehlfeldi, Tabanus autumnalis, Haematopota pluvialis, Heptatoma pellucens). All extracts prolonged human plasma clotting time in a dose-dependent manner and inhibited thrombin activity in the chromogenic substrate assay. Horsefly SGE did not inhibit factor Xa. Partial purification of SGE proteins using reversed-phase high-pe...

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APA Style

Kazimírová, M., Sulanová, M., Kozánek, M., Takác, P., Labuda, M., & Nuttall, P. A. (2001). Identification of anticoagulant activities in salivary gland extracts of four horsefly species (Diptera, tabanidae). Haemostasis, 31(3-6), 294–305.

MLA Style

Kazimírová, M., et al. “Identification of Anticoagulant Activities in Salivary Gland Extracts of Four Horsefly Species (Diptera, Tabanidae).” Haemostasis, vol. 31, no. 3-6, 2001, pp. 294–305.

Chicago Style

Kazimírová, M, M Sulanová, M Kozánek, P Takác, M Labuda, and PA Nuttall. 2001. “Identification of Anticoagulant Activities in Salivary Gland Extracts of Four Horsefly Species (Diptera, Tabanidae).” Haemostasis 31 (3-6): 294–305.
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