Paraplegia and squamous cell carcinoma of the bladder in young women: findings from a case-control study.

Journal article

A death certificate-based case-control study was conducted on 207 women aged 25-44 who died of bladder cancer in England and Wales in the period 1971-89 and 411 controls matched on sex, year of death and age at death. An odds ratio of 12.0 (95% CI 1.5-99.7) was found for women with a history of paraplegia. Four of the six paraplegic women were reported to have had squamous cell carcinoma of the bladder compared with only 19 of the 201 non-paraplegic women. These findings suggest that squamous cell carcinomas of the bladder, especially in paraplegics, may be the result of chronic urinary tract infection.

Authors: Dolin, P; Darby, S; Beral, V

• Publication status: Published
• Journal: British journal of cancer
• Volume: 70
• Issue: 1
• Pages: 167-168
• Publication date: 1994-07-01
• DOI: 10.1038/bjc.1994.269
• EISSN: 1532-1827
• ISSN: 0007-0920
• Language: English
• Keywords: Case-Control Studies; Humans; Urinary Tract Infections; Carcinoma, Squamous Cell; Adult; Death Certificates; Urinary Bladder Neoplasms; Female; Confidence Intervals; Odds Ratio; Paraplegia; England; Matched-Pair Analysis; Wales