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Prevalence of antifolate resistance mutations in Plasmodium falciparum isolates in Afghanistan.

Abstract:

BACKGROUND: Artesunate plus sulphadoxine-pyrimethamine (AS+SP) is now first-line treatment for Plasmodium falciparum infection in several south Asian countries, including Afghanistan. Molecular studies provide a sensitive means to investigate the current state of drug susceptibility to the SP component, and can also provide information on the likely efficacy of other potential forms of artemisinin-combination therapy. METHODS: During the years 2007 to 2010, 120 blood spots from patients with ...

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Publication status:
Published
Peer review status:
Peer reviewed
Version:
Publisher's version

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Publisher copy:
10.1186/1475-2875-12-96

Authors


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Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Medicine, Thailand/Laos MOP
Role:
Author
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Li Ka Shing Foundation Ltd More from this funder
Wellcome Trust More from this funder
Publisher:
BioMed Central Ltd. Publisher's website
Journal:
Malar J Journal website
Volume:
12
Issue:
1
Pages:
Article: 96
Publication date:
2013-01-01
DOI:
EISSN:
1475-2875
ISSN:
1475-2875
URN:
uuid:40b58175-c229-4c8c-9495-a68bfd97fffc
Source identifiers:
390795
Local pid:
pubs:390795

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