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Journal article

Modafinil for the treatment of fatigue in lung cancer: results of a placebo-controlled, double-blind, randomized trial.

Abstract:

PURPOSE: Fatigue is a distressing symptom occurring in more than 60% of patients with cancer. The CNS stimulants modafinil and methylphenidate are recommended for the treatment of cancer-related fatigue, despite a limited evidence base. We aimed to evaluate the efficacy and tolerability of modafinil in the management of fatigue in patients with non-small-cell lung cancer (NSCLC). PATIENTS AND METHODS: Adults with advanced NSCLC and performance status of 0 to 2, who were not treated with chemo...

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Publication status:
Published

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Publisher copy:
10.1200/jco.2013.54.4346

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Institution:
University of Oxford
Department:
Oxford, MSD, Oncology
Role:
Author
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Publisher:
American Society of Clinical Oncology
Journal:
Journal of clinical oncology : official journal of the American Society of Clinical Oncology
Volume:
32
Issue:
18
Pages:
1882-1888
Publication date:
2014-06-05
DOI:
EISSN:
1527-7755
ISSN:
0732-183X
URN:
uuid:4098155e-1f2b-4a9e-8ea8-8315d6f87df8
Source identifiers:
463015
Local pid:
pubs:463015

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