- Abstract:
-
Submicrometre size spheres prepared from biocompatible polymers are becoming increasingly popular in drug and gene delivery. This paper describes the preparation of polymeric spheres with a mean diameter of 0.4 μm with a polydispersivity index of 8%, using coaxial electrohydrodynamic atomization (CEHDA) microbubbling. An 18 wt.% solution of polymethylsilsesquioxane, a hydrophobic biocompatible polymer, was subjected to CEHDA microbubbling by passing air through the inner needle and polymer so...
Expand abstract - Journal:
- International journal of pharmaceutics
- Volume:
- 404
- Issue:
- 1-2
- Pages:
- 110-115
- Publication date:
- 2011-02-05
- DOI:
- EISSN:
-
1873-3476
- ISSN:
-
0378-5173
- URN:
-
uuid:408c307d-ac08-4a99-9e4d-e8bc703cc374
- Source identifiers:
-
327749
- Local pid:
- pubs:327749
- Copyright date:
- 2011
Journal article
Electrohydrodynamic preparation of polymeric drug-carrier particles: mapping of the process.
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