Journal article
Orchestration of the spindle assembly checkpoint by CDK1‐cyclin B1
- Abstract:
-
In mitosis, the spindle assembly checkpoint (SAC) monitors the formation of microtubule‐kinetochore attachments during capture of chromosomes by the mitotic spindle. Spindle assembly is complete once there are no longer any unattached kinetochores. Here, we will discuss the mechanism and key components of spindle checkpoint signalling. Unattached kinetochores bind the principal spindle checkpoint kinase monopolar spindle 1 (MPS1). MPS1 triggers the recruitment of other spindle checkpoint prot...
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- Publication status:
- Published
- Peer review status:
- Peer reviewed
Actions
Authors
Funding
Bibliographic Details
- Publisher:
- Wiley Publisher's website
- Journal:
- FEBS Letters Journal website
- Volume:
- 593
- Issue:
- 20
- Pages:
- 2889-2907
- Publication date:
- 2019-09-13
- Acceptance date:
- 2019-08-19
- DOI:
- EISSN:
-
1873-3468
- ISSN:
-
0014-5793
- Pmid:
-
31469407
Item Description
- Language:
- English
- Keywords:
- Pubs id:
-
pubs:1049947
- UUID:
-
uuid:407467f6-55ff-40eb-adab-dd5886655bed
- Local pid:
- pubs:1049947
- Source identifiers:
-
1049947
- Deposit date:
- 2019-09-12
Terms of use
- Copyright holder:
- Federation of European Biochemical Societies
- Copyright date:
- 2019
- Rights statement:
- © 2019 Federation of European Biochemical Societies.
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