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Genetically restricted and unrestricted antigen specific helper factors

Abstract:

Some human antigen specific helper factors (HF) derived from long term human T helper cell lines are genetically restricted in their action. Other human HF's, derived from 4-6 day cultures, are capable of activating mouse spleen cell cultures, and hence are not xenogeneically restricted. While it is possible that these results suggest a heterogeneity of HF, we have also found that some long term lines make both antigen specific HF and non specific factors. In this case the whole supernatant a...

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Institution:
University of Oxford
Division:
MSD
Department:
NDORMS
Role:
Author
Journal:
Behring Institute Mitteilungen
Volume:
No. 70
Pages:
196-199
Publication date:
1982-01-01
ISSN:
0301-0457
Source identifiers:
94234
Language:
English
Pubs id:
pubs:94234
UUID:
uuid:405e56fb-0d87-4f6c-b1f3-78f9bc7c6915
Local pid:
pubs:94234
Deposit date:
2012-12-20

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