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The exact science of stroke thrombolysis and the quiet art of patient selection.

Abstract:

The science of metric-based patient stratification for intravenous thrombolysis, revolutionized by the landmark National Institute of Neurological Disorders and Stroke trial, has transformed acute ischaemic stroke therapy. Recanalization of an occluded artery produces tissue reperfusion that unequivocally improves outcome and function in patients with acute ischaemic stroke. Recanalization can be achieved mainly through intravenous thrombolysis, but other methods such as intra-arterial thromb...

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Publication status:
Published

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Publisher copy:
10.1093/brain/awt201

Authors


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Institution:
University of Oxford
Department:
Oxford
Role:
Author
More by this author
Institution:
University of Oxford
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
RDM
Sub department:
Stroke and Geratology
Role:
Author
Journal:
Brain : a journal of neurology
Volume:
136
Issue:
Pt 12
Pages:
3528-3553
Publication date:
2013-12-01
DOI:
EISSN:
1460-2156
ISSN:
0006-8950
Source identifiers:
429243
Language:
English
Keywords:
Pubs id:
pubs:429243
UUID:
uuid:405cd6b2-ddf4-40c4-b9bd-8930a65d5b4e
Local pid:
pubs:429243
Deposit date:
2014-08-21

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