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Embryonic stem cells and the challenge of transplantation tolerance.

Abstract:

Isolated from early blastocysts, embryonic stem (ES) cells capture the brief moment of pluripotency in the developing embryo, as evidenced by their differentiation into many somatic cell types in vitro. Although these properties might help meet the growing demand for 'spare parts' to replace diseased or worn-out tissues, their use in so-called cell replacement therapy (CRT) poses several challenges, not least of which is the prevention of their subsequent rejection. Here we explore the notion...

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Publication status:
Published

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Publisher copy:
10.1016/j.it.2004.07.005

Authors


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Institution:
University of Oxford
Department:
Oxford, MSD, Pathology Dunn School
Role:
Author
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, Pathology Dunn School
Role:
Author
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, Pathology Dunn School
Role:
Author
Journal:
Trends in immunology
Volume:
25
Issue:
9
Pages:
465-470
Publication date:
2004-09-05
DOI:
EISSN:
1471-4981
ISSN:
1471-4906
URN:
uuid:4039f60e-807e-4d54-88aa-4f060595a27d
Source identifiers:
19671
Local pid:
pubs:19671

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