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Modelling nutrient transport in hollow fibre membrane bioreactors for growing three-dimensional bone tissue

Abstract:

Recent experimental studies suggest that hollow fibre membrane bioreactors (HFMBs) may be used to grow three-dimensional (3D) bone tissue, which may then be implanted into patients to repair skeletal defects. It has become necessary to develop a theoretical framework that elucidates the quantitative relationships between the cell environment and tissue behaviour in HFMBs in order to guide the design of effective bone tissue engineering protocols. Online measurements of the important flow and ...

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Publication status:
Published

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Authors


Triffitt, JT More by this author
Journal:
JOURNAL OF MEMBRANE SCIENCE
Volume:
272
Issue:
1-2
Pages:
169-178
Publication date:
2006-03-15
DOI:
ISSN:
0376-7388
URN:
uuid:40072feb-7bb9-48e5-8d06-12e2f844e71d
Source identifiers:
62052
Local pid:
pubs:62052

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