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Journal article

Rapid diastereocontrolled synthesis of 2,2,5-trisubstituted pyrrolidines.

Abstract:: 2,2,5-Trisubstituted pyrrolidines are available from allylic pyroglutamates by Ireland-Claisen ester rearrangement followed by Eschenmoser sulfide contraction and reduction in a highly diastereoselective and efficient sequence. Some of the products from this sequence exhibit activity against S. aureus, but are much less active against E. coli.

Publication status:: Published

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APA Style

Chandan, N., & Moloney, M. (2008). Rapid diastereocontrolled synthesis of 2,2,5-trisubstituted pyrrolidines. Organic and Biomolecular Chemistry, 6(20), 3664–3666.

MLA Style

Chandan, N., and M. Moloney. “Rapid Diastereocontrolled Synthesis of 2,2,5-Trisubstituted Pyrrolidines.” Organic and Biomolecular Chemistry, vol. 6, no. 20, 2008, pp. 3664–66.

Chicago Style

Chandan, N, and M Moloney. 2008. “Rapid Diastereocontrolled Synthesis of 2,2,5-Trisubstituted Pyrrolidines.” Organic and Biomolecular Chemistry 6 (20): 3664–66.
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Publisher copy:: 10.1039/b811642c

Authors

+ Chandan, N More by this author

Role:

Author

+ Moloney, M More by this author

Institution:

University of Oxford

Division:

MPLS

Department:

Chemistry

Sub department:

Organic Chemistry

Role:

Author

Bibliographic Details

Journal:: Organic and biomolecular chemistry
Volume:: 6
Issue:: 20
Pages:: 3664-3666
Publication date:: 2008-10-01
DOI:: 10.1039/b811642c
EISSN:: 1477-0539
ISSN:: 1477-0520

Item Description

Language:: English
Pubs id:: pubs:34413
UUID:: uuid:400156be-66b0-41f6-bab0-26a92d430ba5
Local pid:: pubs:34413
Source identifiers:: 34413
Deposit date:: 2012-12-19

Terms of use

Copyright date:: 2008

Licence:: Terms and Conditions of Use for Oxford University Research Archive

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