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Fluorescence labelling of carbohydrates with 2-aminobenzamide (2AB)

Abstract:

2-Aminobenzamide (2AB) is a common fluorescence label attached to reducing oligosaccharides by a reductive amination procedure. Chemical investigation of the published literature procedure reveals labelling occurs by the expected mechanism for both protected and unprotected glucose derivatives to yield open-chain carbohydrates rather than result in the formation of any heterocyclic materials. Pentenyl glucosides may also be readily attached to the 2AB label by a sequence of dihydroxylation, p...

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Publication status:
Published

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Institution:
University of Oxford
Department:
Oxford, MSD, Biochemistry
Role:
Author
Journal:
TETRAHEDRON-ASYMMETRY
Volume:
11
Issue:
24
Pages:
4985-4994
Publication date:
2000-12-15
DOI:
ISSN:
0957-4166
URN:
uuid:40002bf9-0e6e-48e6-aeda-39240ecef6d6
Source identifiers:
100928
Local pid:
pubs:100928
Language:
English

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