Collaborative Cross mice and their power to map host susceptibility to Aspergillus fumigatus infection

Journal article

The Collaborative Cross (CC) is a genetic reference panel of recombinant inbred lines of mice, designed for the dissection of complex traits and gene networks. Each line is independently descended from eight genetically diverse founder strains such that the genomes of the CC lines, once fully inbred, are fine-grained homozygous mosaics of the founder haplotypes. We present an analysis of 120 CC lines, from a cohort of the CC bred at Tel Aviv University in collaboration with the University of ...

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Authors: Durrant, C; Tayem, H; Yalcin, B; Cleak, J; Goodstadt, L

• Journal: Genome Research
• Volume: 21
• Issue: 8
• Pages: 1239-1248
• Publication date: 2011-08-01
• DOI: 10.1101/gr.118786.110
• EISSN: 1549-5469
• ISSN: 1088-9051
• Language: English