Journal article
Neural crest migration is driven by a few trailblazer cells with a unique molecular signature narrowly confined to the invasive front.
- Abstract:
-
Neural crest (NC) cell migration is crucial to the formation of peripheral tissues during vertebrate development. However, how NC cells respond to different microenvironments to maintain persistence of direction and cohesion in multicellular streams remains unclear. To address this, we profiled eight subregions of a typical cranial NC cell migratory stream. Hierarchical clustering showed significant differences in the expression profiles of the lead three subregions compared with newly emerge...
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- Publication status:
- Published
- Peer review status:
- Peer reviewed
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Authors
Funding
+ Engineering and Physical Sciences Research Council
More from this funder
Funding agency for:
Schumacher, L
Grant:
University of Oxford’s Doctoral Training Centre Life Science Interface Studentship
Bibliographic Details
- Publisher:
- Company of Biologists Publisher's website
- Journal:
- Development Journal website
- Volume:
- 142
- Issue:
- 11
- Pages:
- 2014-2025
- Publication date:
- 2015-05-26
- DOI:
- EISSN:
-
1477-9129
- ISSN:
-
0950-1991
Item Description
- Language:
- English
- Keywords:
- Pubs id:
-
pubs:523260
- UUID:
-
uuid:3ffd22a2-82f3-4f91-a760-44e6ddc487b2
- Local pid:
- pubs:523260
- Source identifiers:
-
523260
- Deposit date:
- 2016-02-10
Terms of use
- Copyright holder:
- The Company of Biologists
- Copyright date:
- 2015
- Notes:
- © 2015. Published by The Company of Biologists Ltd. This is the publisher's version of the article. The final version is available online from the Company of Biologists at: [10.1242/dev.117507]
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