Thesis
Stereochemical aspects of the interaction between isomerases and their substrates
- Abstract:
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The work presented in this thesis is concerned with the mechanism of two enzymes of the glycolytic pathway, each of which catalyzes an aldose-ketose isomerization.
The first part of the thesis deals with triosephosphate isomerase, which catalyzes the interconversion of dihydroxyacetone phosphate and D-glyceraldehyde 3-phosphate. A mechanism has been proposed for this reaction that involves the transfer of a proton between carbon centres of the substrates, and an enzyme-boun...
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Authors
Bibliographic Details
- Publication date:
- 1976
- Type of award:
- DPhil
- Level of award:
- Doctoral
- Awarding institution:
- University of Oxford
- URN:
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uuid:3ff91fc2-988b-43d7-95a1-d5a685e0e002
- Local pid:
- td:601870746
Item Description
- Language:
- English
Terms of use
- Copyright holder:
- Webb, Martin R.
- Copyright date:
- 1976
- Notes:
- This thesis was digitised thanks to the generosity of Dr Leonard Polonsky
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