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Hepatic copper distribution in primary biliary cirrhosis shown by the scanning proton microprobe.

Abstract:

A number of conditions are associated with abnormalities of trace metal handling by the liver. We report the application of the Oxford scanning proton microprobe to the analysis of hepatic copper in one such condition, primary biliary cirrhosis. The scanning proton microprobe analyses conventional tissue sections (5-10 micron thickness) and produces simultaneous elemental distribution maps of biologically relevant elements with a spatial resolution of 1 micron and a detection limit better tha...

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Publication status:
Published

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Publisher copy:
10.1136/jcp.38.6.653

Authors


Journal:
Journal of clinical pathology
Volume:
38
Issue:
6
Pages:
653-658
Publication date:
1985-06-01
DOI:
EISSN:
1472-4146
ISSN:
0021-9746
Source identifiers:
27829
Language:
English
Keywords:
Pubs id:
pubs:27829
UUID:
uuid:3fefcfd2-cbe2-449e-be7e-ed166143aa2f
Local pid:
pubs:27829
Deposit date:
2012-12-19

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