Journal article icon

Journal article

Transient foamy virus vector production by adenovirus vectors.

Abstract:

The genome of the prototype foamy virus (PFV) has been introduced into an adenoviral/PFV hybrid vector and tested for stable in vitro gene transfer. Three different adenoviruses are used to encode: (i) the PFV structural genes gag and pol (Ad-GagPolDeltaPacI); (ii) the PFV structural gene env (Ad-Env); and (iii) the PFV vector genome (Ad-MD9) encoding the transgene (the enhanced green fluorescent protein (eGFP) gene). Following cotransduction by the three adenoviruses, the target cells become...

Expand abstract

Actions


Access Document


Publisher copy:
10.1038/sj.gt.3302177

Authors


More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, Pathology Dunn School
Role:
Author
Journal:
Gene therapy
Volume:
11
Issue:
3
Pages:
310-316
Publication date:
2004-02-05
DOI:
EISSN:
1476-5462
ISSN:
0969-7128
URN:
uuid:3feab37e-68d9-4c96-9105-4ea683ef667f
Source identifiers:
237022
Local pid:
pubs:237022

Terms of use


Metrics


Views and Downloads






If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP