- Abstract:
-
The genome of the prototype foamy virus (PFV) has been introduced into an adenoviral/PFV hybrid vector and tested for stable in vitro gene transfer. Three different adenoviruses are used to encode: (i) the PFV structural genes gag and pol (Ad-GagPolDeltaPacI); (ii) the PFV structural gene env (Ad-Env); and (iii) the PFV vector genome (Ad-MD9) encoding the transgene (the enhanced green fluorescent protein (eGFP) gene). Following cotransduction by the three adenoviruses, the target cells become...
Expand abstract - Publisher copy:
- 10.1038/sj.gt.3302177
-
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- Journal:
- Gene therapy
- Volume:
- 11
- Issue:
- 3
- Pages:
- 310-316
- Publication date:
- 2004-02-05
- DOI:
- EISSN:
-
1476-5462
- ISSN:
-
0969-7128
- URN:
-
uuid:3feab37e-68d9-4c96-9105-4ea683ef667f
- Source identifiers:
-
237022
- Local pid:
- pubs:237022
- Copyright date:
- 2004
Journal article
Transient foamy virus vector production by adenovirus vectors.
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