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Journal article

Genetics and multiple sclerosis: an overview.

Abstract:

There is evidence to support the view that multiple sclerosis is a complex trait determined by both genetic and environmental factors. The genetic component is reflected in the higher rate of concordance in monozygotic versus dizygotic twins and in familial recurrence risk data. These data fit best with oligogenic hypotheses encompassing epistatic interactions. However, confirmation will require comprehensive linkage studies using techniques that can rapidly screen the entire genome. The numb...

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Publication status:
Published

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Publisher copy:
10.1002/ana.410360705

Authors


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Institution:
University of Oxford
Division:
MSD
Department:
NDM
Sub department:
Human Genetics Wt Centre
Role:
Author
Journal:
Annals of neurology
Volume:
36 Suppl
Issue:
SUPPL.
Pages:
S12-S14
Publication date:
1994-01-01
DOI:
EISSN:
1531-8249
ISSN:
0364-5134
Source identifiers:
35768

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