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Macrophage pattern recognition receptors in immunity, homeostasis and self tolerance.

Abstract:
Macrophages, a major component of innate immune defence, express a large repertoire of different classes of pattern recognition receptors and other surface antigens which determine the immunologic and homeostatic potential of these versatile cells. In the light of present knowledge ofmacrophage surface antigens, we discuss self versus nonself recognition, microbicidal effector functions and self tolerance in the innate immune system.
Publication status:
Published

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Publisher copy:
10.1109/TENCON.2009.5396176

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Institution:
University of Oxford
Department:
Oxford, MSD, Pathology Dunn School
Role:
Author
Journal:
Advances in experimental medicine and biology
Volume:
653
Pages:
1-14
Publication date:
2009-01-01
DOI:
ISSN:
0065-2598
URN:
uuid:3fdfd929-ecd2-47a8-ae34-f5b8f730aa00
Source identifiers:
21512
Local pid:
pubs:21512

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