Journal article icon

Journal article

Involvement of pertussis toxin-sensitive and -insensitive GTP-binding proteins in luteinizing hormone exocytosis distal to second messenger generation.

Abstract:

Inhibition of luteinizing hormone (LH) exocytosis by guanosine 5'-[gamma-thio]triphosphate (GTP gamma S) in permeabilized pituitary cells has indicated the involvement of one or more GTP-binding proteins in the exocytotic mechanism distal to second messenger generation. We now report that two inhibitory sites of action of GTP gamma S can be distinguished by their dependence on GTP gamma S concentration and their sensitivity to pertussis toxin. Ca(2+)-stimulated exocytosis was half-maximally i...

Expand abstract

Actions


Access Document


Authors


More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, Pathology Dunn School
Role:
Author
Journal:
Cellular signalling
Volume:
4
Issue:
4
Pages:
379-384
Publication date:
1992-07-05
DOI:
EISSN:
1873-3913
ISSN:
0898-6568
URN:
uuid:3fcf1fdd-6d6b-4eef-9911-0dba592e0597
Source identifiers:
19044
Local pid:
pubs:19044

Terms of use


Metrics



If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP