- Abstract:
-
Inhibition of luteinizing hormone (LH) exocytosis by guanosine 5'-[gamma-thio]triphosphate (GTP gamma S) in permeabilized pituitary cells has indicated the involvement of one or more GTP-binding proteins in the exocytotic mechanism distal to second messenger generation. We now report that two inhibitory sites of action of GTP gamma S can be distinguished by their dependence on GTP gamma S concentration and their sensitivity to pertussis toxin. Ca(2+)-stimulated exocytosis was half-maximally i...
Expand abstract - Publisher copy:
- 10.1016/0898-6568(92)90032-4
-
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- Journal:
- Cellular signalling
- Volume:
- 4
- Issue:
- 4
- Pages:
- 379-384
- Publication date:
- 1992-07-05
- DOI:
- EISSN:
-
1873-3913
- ISSN:
-
0898-6568
- URN:
-
uuid:3fcf1fdd-6d6b-4eef-9911-0dba592e0597
- Source identifiers:
-
19044
- Local pid:
- pubs:19044
- Copyright date:
- 1992
Journal article
Involvement of pertussis toxin-sensitive and -insensitive GTP-binding proteins in luteinizing hormone exocytosis distal to second messenger generation.
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