- Abstract:
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This thesis focuses on the development of a novel nucleophilic 18F-fluorination of (hetero)arenes and of a rapid screening experiment to facilitate the application of this reaction to complex heterocyclic targets of medicinal importance.
Chapter 1 introduces the use of molecules labelled with fluorine-18 as tracers in positron emission tomography and reviews methods for the preparation of [18F]fluoroarenes published prior to the start of the wo...
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- Type of award:
- DPhil
- Level of award:
- Doctoral
- Awarding institution:
- University of Oxford
- Language:
- English
- Keywords:
- Subjects:
- Copyright date:
- 2017
Thesis
Copper-mediated nucleophilic 18F-radiolabelling of (hetero)arenes for applications in positron emission tomography
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