Thesis
Copper-mediated nucleophilic 18F-radiolabelling of (hetero)arenes for applications in positron emission tomography
- Abstract:
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This thesis focuses on the development of a novel nucleophilic 18F-fluorination of (hetero)arenes and of a rapid screening experiment to facilitate the application of this reaction to complex heterocyclic targets of medicinal importance.
Chapter 1 introduces the use of molecules labelled with fluorine-18 as tracers in positron emission tomography and reviews methods for the preparation of [18F]fluoroarenes published prior to the start of the wo...
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Funding
BBRSC
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Bibliographic Details
- Type of award:
- DPhil
- Level of award:
- Doctoral
- Awarding institution:
- University of Oxford
Item Description
- Language:
- English
- Keywords:
- Subjects:
- UUID:
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uuid:3fbaaf65-a9a0-4522-8310-6acf29e3ff7c
- Deposit date:
- 2018-07-05
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Terms of use
- Copyright holder:
- Taylor, N
- Copyright date:
- 2017
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