Journal article
Simian Virus 40 depends on ER protein folding and quality control factors for entry into host cells.
- Abstract:
-
Cell entry of Simian Virus 40 (SV40) involves caveolar/lipid raft-mediated endocytosis, vesicular transport to the endoplasmic reticulum (ER), translocation into the cytosol, and import into the nucleus. We analyzed the effects of ER-associated processes and factors on infection and on isolated viruses and found that SV40 makes use of the thiol-disulfide oxidoreductases, ERp57 and PDI, as well as the retrotranslocation proteins Derlin-1 and Sel1L. ERp57 isomerizes specific interchain disulfid...
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- Publication status:
- Published
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- Publisher copy:
- 10.1016/j.cell.2007.09.038
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Bibliographic Details
- Journal:
- Cell
- Volume:
- 131
- Issue:
- 3
- Pages:
- 516-529
- Publication date:
- 2007-11-01
- DOI:
- EISSN:
-
1097-4172
- ISSN:
-
0092-8674
- Source identifiers:
-
95890
Item Description
- Language:
- English
- Keywords:
- Pubs id:
-
pubs:95890
- UUID:
-
uuid:3fb72e46-6d9f-41c8-ada2-41d8af4b9950
- Local pid:
- pubs:95890
- Deposit date:
- 2012-12-19
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- Copyright date:
- 2007
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