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Imaging of the vulnerable carotid plaque: biological targeting of inflammation in atherosclerosis using iron oxide particles and MRI.

Abstract:

OBJECTIVES: Identification of those patients with high-risk asymptomatic carotid plaques remains an elusive but essential step in stroke prevention. Inflammation is a key process in plaque destabilization and the propensity of atherosclerotic lesions to cause clinical sequelae. There is currently no clinical imaging technique available to assess the degree of inflammation associated with plaques. This study aims at visualizing and characterizing atherosclerosis using antibody-conjugated super...

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Publisher copy:
10.1016/j.ejvs.2014.01.017

Authors


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Institution:
University of Oxford
Department:
Oxford, MSD, NDORMS, BHF Centre of Research Excellence
Role:
Author
Publisher:
W.B. Saunders Ltd
Journal:
European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery
Volume:
47
Issue:
5
Pages:
462-469
Publication date:
2014-05-05
DOI:
EISSN:
1532-2165
ISSN:
1078-5884
URN:
uuid:3fae0b89-e862-4909-8d95-ad498fa2ff25
Source identifiers:
451194
Local pid:
pubs:451194

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