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Journal article

The molecular basis of α-thalassemia.

Abstract:

The globin gene disorders including the thalassemias are among the most common human genetic diseases with more than 300,000 severely affected individuals born throughout the world every year. Because of the easy accessibility of purified, highly specialized, mature erythroid cells from peripheral blood, the hemoglobinopathies were among the first tractable human molecular diseases. From the 1970s onward, the analysis of the large repertoire of mutations underlying these conditions has elucid...

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Publication status:
Published

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Publisher copy:
10.1101/cshperspect.a011718

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Institution:
University of Oxford
Department:
Oxford, MSD, RDM, Molecular Medicine, Biomedical Research Centre
Journal:
Cold Spring Harbor perspectives in medicine
Volume:
3
Issue:
1
Pages:
a011718
Publication date:
2013-01-05
DOI:
EISSN:
2157-1422
ISSN:
2157-1422
URN:
uuid:3f940646-966c-4934-9da9-6e094a2813a2
Source identifiers:
369885
Local pid:
pubs:369885

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