High affinity agonist binding to cloned 5-hydroxytryptamine2 receptors is not sensitive to GTP analogs.

Szele, FG; Pritchett, DB

Abstract:

Agonists for GTP-binding protein (G protein)-coupled receptors are thought to bind with high affinity to the complex of receptor and G protein. Nonhydrolyzable GTP analogs have been shown to disrupt this complex and reduce the binding affinity for many agonists. Antagonists are thought to bind to the receptor whether or not it is coupled to the G protein, and therefore binding remains unchanged in the presence of GTP analogs. The binding of the serotonin 5-hydroxytryptamine (5-HT)2 receptor a...

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APA Style

Szele, F. G., & Pritchett, D. B. (1993). High affinity agonist binding to cloned 5-hydroxytryptamine2 receptors is not sensitive to GTP analogs. Molecular Pharmacology, 43(6), 915–920.

MLA Style

Szele, F. G., and D. B. Pritchett. “High Affinity Agonist Binding to Cloned 5-hydroxytryptamine2 Receptors Is Not Sensitive to GTP Analogs.” Molecular Pharmacology, vol. 43, no. 6, Molecular pharmacology, 1993, pp. 915–20.

Chicago Style

Szele, FG, and DB Pritchett. 1993. “High Affinity Agonist Binding to Cloned 5-hydroxytryptamine2 Receptors Is Not Sensitive to GTP Analogs.” Molecular Pharmacology 43 (6): 915–20.
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