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Temazepam at high altitude reduces periodic breathing without impairing next-day performance: a randomized cross-over double-blind study.

Abstract:

The aim of the study was to examine the efficacy and safety of temazepam on nocturnal oxygenation and next-day performance at altitude. A double-blind, randomized, cross-over trial was performed in Thirty-three healthy volunteers. Volunteers took 10 mg of temazepam and placebo in random order on two successive nights soon after arrival at 5000 m, following a 17-day trek from 410 m. Overnight SaO(2) and body movements, and next-day reaction time, maintenance of wakefulness and cognition were a...

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Publication status:
Published

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Journal:
Journal of sleep research
Volume:
15
Issue:
4
Pages:
445-454
Publication date:
2006-12-01
DOI:
EISSN:
1365-2869
ISSN:
0962-1105
Source identifiers:
71446
Language:
English
Keywords:
Pubs id:
pubs:71446
UUID:
uuid:3f859ef3-baf9-4d0d-8437-da8a6f2970ee
Local pid:
pubs:71446
Deposit date:
2012-12-19

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