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Journal article

Macrophage-mediated biodegradation of poly(DL-lactide-co-glycolide) in vitro.

Abstract:

Biodegradation of poly-DL-lactide-co-glycolide (PLGA) both in vitro and in vivo has been well documented. However, the roles that macrophages and their fused multinucleated giant cells (MNGCs) play in this biodegradation are still unclear. The current study aimed to investigate macrophage-mediated biodegradation of PLGA thin films and of PLGA composites with hydroxyapatite (HA) and tricalcium phosphate (TCP) ceramic powders in vitro using a murine macrophage cell line (RAW 264.7). The interac...

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Publication status:
Published

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Publisher copy:
10.1002/jbm.a.30853

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Journal:
Journal of biomedical materials research. Part A
Volume:
79
Issue:
3
Pages:
582-590
Publication date:
2006-12-01
DOI:
EISSN:
1552-4965
ISSN:
1549-3296
Source identifiers:
62019
Language:
English
Keywords:
Pubs id:
pubs:62019
UUID:
uuid:3f7b1d3c-0041-4089-b675-d317b622fd0b
Local pid:
pubs:62019
Deposit date:
2013-11-16

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