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Modeling dispersion in arterial spin labeling: Validation using dynamic angiographic measurements

Abstract:

A major assumption in arterial spin labeling (ASL) MRI perfusion quantification is the time course of the signal on arrival in the capillary network. The normally assumed square label profile is not preserved during transit of the label through the vasculature. This change in profile can be attributed to a number of effects collectively denoted as dispersion. A number of models for this effect have been proposed, but they have been difficult to validate. In this study ASL data acquired whilst...

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Publisher copy:
10.1002/mrm.24260

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Institution:
University of Oxford
Department:
Oxford, MPLS, Engineering Science
Chappell, MA More by this author
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Institution:
University of Oxford
Department:
Oxford, MSD, Psychiatry
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Neuroscience
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Journal:
Magnetic Resonance in Medicine
Volume:
69
Issue:
2
Pages:
563-570
Publication date:
2013-02-01
DOI:
EISSN:
1522-2594
ISSN:
0740-3194
URN:
uuid:3f6c2ce9-8f7d-4bfd-9acb-80ef319aa86a
Source identifiers:
384888
Local pid:
pubs:384888

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