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Journal article

Double diastereoselective SuperQuat glycolate aldol reactions: application to the asymmetric synthesis of polyfunctionalised lactones.

Abstract:: Polyfunctionalised lactones with up to five contiguous stereocentres may be prepared with high stereocontrol by a double diastereoselective aldol protocol with protected homochiral alpha,beta-dihydroxy- or alpha,beta-gamma-trihydroxyaldehydes and a chiral glycolate oxazolidinone, followed by subsequent O-desilylation and lactonisation.

Publication status:: Published

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APA Style

Davies, S., Nicholson, R., & Smith, A. (2004). Double diastereoselective SuperQuat glycolate aldol reactions: application to the asymmetric synthesis of polyfunctionalised lactones. Organic and Biomolecular Chemistry, 2(22), 3385–3400.

MLA Style

Davies, S., et al. “Double Diastereoselective SuperQuat Glycolate Aldol Reactions: Application to the Asymmetric Synthesis of Polyfunctionalised Lactones.” Organic and Biomolecular Chemistry, vol. 2, no. 22, 2004, pp. 3385–400.

Chicago Style

Davies, S, R Nicholson, and A Smith. 2004. “Double Diastereoselective SuperQuat Glycolate Aldol Reactions: Application to the Asymmetric Synthesis of Polyfunctionalised Lactones.” Organic and Biomolecular Chemistry 2 (22): 3385–3400.
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Publisher copy:: 10.1039/b411724g

Authors

+ Davies, S More by this author

Institution:

University of Oxford

Division:

MPLS

Department:

Chemistry

Sub department:

Organic Chemistry

Role:

Author

+ Nicholson, R More by this author

Role:

Author

+ Smith, A More by this author

Role:

Author

Bibliographic Details

Journal:: Organic and biomolecular chemistry
Volume:: 2
Issue:: 22
Pages:: 3385-3400
Publication date:: 2004-11-01
DOI:: 10.1039/b411724g
EISSN:: 1477-0539
ISSN:: 1477-0520

Item Description

Language:: English
Keywords:: Chemistry, Organic

Models, Chemical

Lactones

Aldehydes

Stereoisomerism

Glycolates
Pubs id:: pubs:110547
UUID:: uuid:3f5e5d45-629d-44f3-a9a5-9094686e3abf
Local pid:: pubs:110547
Source identifiers:: 110547
Deposit date:: 2012-12-19

Terms of use

Copyright date:: 2004

Licence:: Terms and Conditions of Use for Oxford University Research Archive

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