Journal article
B cell repopulation after alemtuzumab induction-transient increase in transitional B cells and long-term dominance of naive B cells.
- Abstract:
-
In organ transplantation, the composition of the B-cell compartment is increasingly identified as an important determinant for graft outcome. Whereas naïve and transitional B cells have been associated with long-term allograft survival and operational tolerance, memory B cells have been linked to decreased allograft survival. Alemtuzumab induction therapy effectively depletes B cells, but is followed by rapid repopulation up to levels exceeding base line. The characteristics of the repopulati...
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- Publication status:
- Published
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Bibliographic Details
- Journal:
- American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons
- Volume:
- 12
- Issue:
- 7
- Pages:
- 1784-1792
- Publication date:
- 2012-07-01
- DOI:
- EISSN:
-
1600-6143
- ISSN:
-
1600-6135
Item Description
- Language:
- English
- Keywords:
- Pubs id:
-
pubs:320280
- UUID:
-
uuid:3f3ffb5a-7ceb-4cab-a72a-49b1f319edf3
- Local pid:
- pubs:320280
- Source identifiers:
-
320280
- Deposit date:
- 2013-11-16
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- Copyright date:
- 2012
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