Global epidemiology of Sickle haemoglobin in neonates: A contemporary geostatistical model-based map and population estimates

Journal article

Background Reliable estimates of populations affected by diseases are necessary to guide efficient allocation of public health resources. Sickle haemoglobin (HbS) is the most common and clinically significant haemoglobin structural variant, but no contemporary estimates exist of the global populations affected. Moreover, the precision of available national estimates of heterozygous (AS) and homozygous (SS) neonates is unknown. We aimed to provide evidencebased estimates at various scales, wit...

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Authors: Piel, F; Patil, A; Howes, R; Nyangiri, O; Gething, P

• Journal: Lancet
• Volume: 381
• Issue: 9861
• Pages: 142-151
• Publication date: 2013-01-01
• DOI: 10.1016/S0140-6736(12)61229-X
• EISSN: 1474-547X
• ISSN: 0140-6736
• Language: English