Journal article
Kir6.2-containing ATP-sensitive potassium channels protect cortical neurons from ischemic/anoxic injury in vitro and in vivo.
- Abstract:
-
ATP-sensitive potassium (K(ATP)) channels are weak inward rectifiers that appear to play an important role in protecting neurons against ischemic damage. Cerebral stroke is a major health issue, and vulnerability to stroke damage is regional within the brain. Thus, we set out to determine whether K(ATP) channels protect cortical neurons against ischemic insults. Experiments were performed using Kir6.2(-/-) K(ATP) channel knockout and Kir6.2(+/+) wildtype mice. We compared results obtained in ...
Expand abstract
- Publication status:
- Published
Actions
Authors
Bibliographic Details
- Journal:
- Neuroscience
- Volume:
- 144
- Issue:
- 4
- Pages:
- 1509-1515
- Publication date:
- 2007-02-01
- DOI:
- EISSN:
-
1873-7544
- ISSN:
-
0306-4522
- Source identifiers:
-
79159
Item Description
- Language:
- English
- Keywords:
- Pubs id:
-
pubs:79159
- UUID:
-
uuid:3f2952d2-8697-4589-bb0d-47e773e39c08
- Local pid:
- pubs:79159
- Deposit date:
- 2012-12-19
Terms of use
- Copyright date:
- 2007
If you are the owner of this record, you can report an update to it here: Report update to this record