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Journal article

Genotypes and in vivo resistance of Plasmodium falciparum isolates in an endemic region of Iran.

Abstract:

Mutations in the dihydrofolate reductase (DHFR) and dihydropteroate synthase (DHPS) genes of Plasmodium falciparum have been correlated with and used to detect antifolate treatment failure, such as sulfadoxine-pyrimethamine (SP), in regions endemic for malaria. To determine the association between molecular markers of SP resistance and in vivo drug resistance, a quick and simple technique that detects single nucleotide polymorphisms in the DHFR and DHPS genes, using PCR-ELISA and sequence-spe...

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Publication status:
Published

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Publisher copy:
10.1007/s00436-006-0291-z

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Institution:
University of Oxford
Division:
MSD
Department:
NDM
Role:
Author
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Journal:
Parasitology research
Volume:
100
Issue:
3
Pages:
589-592
Publication date:
2007-02-01
DOI:
EISSN:
1432-1955
ISSN:
0932-0113
Source identifiers:
458981
Language:
English
Keywords:
Pubs id:
pubs:458981
UUID:
uuid:3f273b66-2a0a-498a-aaaa-4b21a87444cc
Local pid:
pubs:458981
Deposit date:
2014-05-13

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