- Abstract:
-
A polyspecific Pan-African antivenom has been produced from the plasma of horses immunized with a mixture of the venoms of Echis ocellatus, Bitis arietans and Naja nigricollis, the three most medically important snakes in sub-Saharan Africa. The antivenom is a whole IgG preparation, obtained by caprylic acid precipitation of non-IgG plasma proteins. The antivenom effectively neutralizes the most important toxic activities of the three venoms used in the immunization in standard assays involvi...
Expand abstract - Publication status:
- Published
- Publisher copy:
- 10.1016/j.trstmh.2004.09.014
-
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- Journal:
- Transactions of the Royal Society of Tropical Medicine and Hygiene
- Volume:
- 99
- Issue:
- 6
- Pages:
- 468-475
- Publication date:
- 2005-06-05
- DOI:
- EISSN:
-
1878-3503
- ISSN:
-
0035-9203
- URN:
-
uuid:3f198001-26fb-44bd-9699-1b8556d5162f
- Source identifiers:
-
61022
- Local pid:
- pubs:61022
- Language:
- English
- Keywords:
- Copyright date:
- 2005
Journal article
Pan-African polyspecific antivenom produced by caprylic acid purification of horse IgG: an alternative to the antivenom crisis in Africa.
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