Two-component systems and their co-option for eukaryotic signal transduction.

Journal article

Two-component signaling pathways involve histidine kinases, response regulators, and sometimes histidine-containing phosphotransfer proteins. Prevalent in prokaryotes, these signaling elements have also been co-opted to meet the needs of signal transduction in eukaryotes such as fungi and plants. Here we consider the evolution of such regulatory systems, with a particular emphasis on the roles they play in signaling by the plant hormones cytokinin and ethylene, in phytochrome-mediated percept...

Expand abstract

Authors: Schaller, G; Shiu, S; Armitage, J

• Publication status: Published
• Journal: Current biology : CB
• Volume: 21
• Issue: 9
• Pages: R320-R330
• Publication date: 2011-05-01
• DOI: 10.1016/j.cub.2011.02.045
• EISSN: 1879-0445
• ISSN: 0960-9822
• Language: English
• Keywords: Eukaryotic Cells; Biological Evolution; Cytokinins; Signal Transduction; Models, Biological; Prokaryotic Cells; Light Signal Transduction; Plants; Ethylenes; Circadian Clocks; Protein Kinases