Journal article
Apelin-13 infusion salvages the peri-infarct region to preserve cardiac function after severe myocardial injury
- Abstract:
-
Background: Apelin-13 (A13) regulates cardiac homeostasis. However, the effects and mechanism of A13 infusion after an acute myocardial injury (AMI) have not been elucidated. This study assesses the restorative effects and mechanism of A13 on the peri-infarct region in murine AMI model.
Methods: 51 FVB/N mice (12 weeks, 30 g) underwent AMI. A week following injury, continuous micro-pump infusion of A13 (0.5 μg/g/day) and saline was initiated for 4-...
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- Publication status:
- Published
- Peer review status:
- Peer reviewed
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Bibliographic Details
- Publisher:
- Elsevier Publisher's website
- Journal:
- International Journal of Cardiology Journal website
- Volume:
- 222
- Pages:
- 361-367
- Publication date:
- 2016-08-01
- Acceptance date:
- 2016-07-30
- DOI:
- ISSN:
-
0167-5273
Item Description
- Language:
- English
- Keywords:
- Pubs id:
-
1162111
- Local pid:
- pubs:1162111
- Deposit date:
- 2021-02-18
Terms of use
- Copyright holder:
- Elsevier
- Copyright date:
- 2016
- Rights statement:
- © 2016 Elsevier Ireland Ltd. All rights reserved.
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