- We examined adenomas and cancers from hereditary non-polyposis colorectal cancer (HNPCC) syndrome patients for the presence of frameshift mutations in the smooth-muscle myosin gene, MYH11. Our results show that mutations in MYH11 occur more frequently in cancers than adenomas (P=0.008) and are dependent on microsatellite instability (MSI+).
- Publication status:
- Publisher copy:
- Copyright date:
Smooth-muscle myosin mutations in hereditary non-polyposis colorectal cancer syndrome.
If you are the owner of this record, you can report an update to it here: Report update to this record