Journal article icon

Journal article

Smooth-muscle myosin mutations in hereditary non-polyposis colorectal cancer syndrome.

Abstract:
We examined adenomas and cancers from hereditary non-polyposis colorectal cancer (HNPCC) syndrome patients for the presence of frameshift mutations in the smooth-muscle myosin gene, MYH11. Our results show that mutations in MYH11 occur more frequently in cancers than adenomas (P=0.008) and are dependent on microsatellite instability (MSI+).
Publication status:
Published

Actions


Access Document


Publisher copy:
10.1038/sj.bjc.6604737

Authors


Vickaryous, N More by this author
Polanco-Echeverry, G More by this author
Suraweera, N More by this author
Expand authors...
Journal:
British journal of cancer
Volume:
99
Issue:
10
Pages:
1726-1728
Publication date:
2008-11-05
DOI:
EISSN:
1532-1827
ISSN:
0007-0920
URN:
uuid:3ee59319-a596-4758-a481-30e4667350ed
Source identifiers:
72070
Local pid:
pubs:72070

Terms of use


Metrics



If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP