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Diverse spatial, temporal, and sexual expression of recently duplicated androgen-binding protein genes in Mus musculus

Abstract:

Background: The genes for salivary androgen-binding protein (ABP) subunits have been evolving rapidly in ancestors of the house mouse Mus musculus, as evidenced both by recent and extensive gene duplication and by high ratios of nonsynonymous to synonymous nucleotide substitution rates. This makes ABP an appropriate model system with which to investigate how recent adaptive evolution of paralogous genes results in functional innovation (neofunctionalization). Results: It was our goal to find...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1186/1471-2148-5-40

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Institution:
Butler University (Indianapolis, Indiana)
Department:
Internal Medicine Residency Program,St. Vincent Hospital
Role:
Author
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Institution:
Indiana University School of Medicine
Department:
Department of Medical and Molecular Genetics
Role:
Author
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Institution:
University College London
Role:
Author
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Institution:
University of Oxford
Department:
MRC Functional Genetics Unit
Role:
Author
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Institution:
Butler University (Indianapolis, Indiana)
Department:
Department of Biological Sciences
Role:
Author

Contributors

Publisher:
BioMed Central
Journal:
BMC Evolutionary Biology Journal website
Volume:
5
Article number:
40
Publication date:
2005-01-01
DOI:
ISSN:
1471-2148
Language:
English
Keywords:
Subjects:
UUID:
uuid:3ee2448f-6621-47de-bec4-a998eabcfae0
Local pid:
ora:2286
Deposit date:
2008-09-04

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