Journal article
In vitro and in vivo evaluation of [123I]-VEGF165 as a potential tumor marker.
- Abstract:
-
One of the research challenges in oncology is to develop new biochemical methods for noninvasive tumor therapy evaluation to determine whether the chemotherapeutics is effective. Vascular endothelial growth factor (VEGF) was labeled with radioiodine and evaluated in vitro as well as in vivo, using A2058, a melanoma cell line overexpressing VEGFR-1 and -2. Saturation binding analysis with [(125)I]-VEGF resulted in a K(d) of 0.1 nM. Internalization assays indicate the preserved ligand induced i...
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- Publication status:
- Published
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- Publisher copy:
- 10.1016/j.nucmedbio.2005.03.005
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Bibliographic Details
- Journal:
- Nuclear medicine and biology
- Volume:
- 32
- Issue:
- 5
- Pages:
- 431-436
- Publication date:
- 2005-07-01
- DOI:
- EISSN:
-
1872-9614
- ISSN:
-
0969-8051
- Source identifiers:
-
259094
Item Description
- Language:
- English
- Keywords:
- Pubs id:
-
pubs:259094
- UUID:
-
uuid:3ee0154d-45d7-478b-9c45-ebf427d2732b
- Local pid:
- pubs:259094
- Deposit date:
- 2013-11-17
Terms of use
- Copyright date:
- 2005
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