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Journal article

Implications for collagen binding from the crystallographic structure of fibronectin 6FnI1-2FnII7FnI.

Abstract:

Collagen and fibronectin (FN) are two abundant and essential components of the vertebrate extracellular matrix; they interact directly with cellular receptors and affect cell adhesion and migration. Past studies identified a FN fragment comprising six modules, (6)FnI(1-2)FnII(7-9)FnI, and termed the gelatin binding domain (GBD) as responsible for collagen interaction. Recently, we showed that the GBD binds tightly to a specific site within type I collagen and determined the structure of domai...

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Publication status:
Published

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Publisher copy:
10.1074/jbc.m110.139394

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Journal:
Journal of biological chemistry
Volume:
285
Issue:
44
Pages:
33764-33770
Publication date:
2010-10-01
DOI:
EISSN:
1083-351X
ISSN:
0021-9258
Source identifiers:
196805
Language:
English
Keywords:
Pubs id:
pubs:196805
UUID:
uuid:3edaa457-afd5-4cd0-a195-91ea86ad243a
Local pid:
pubs:196805
Deposit date:
2012-12-19

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