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From stem cell to embryo without centrioles.

Abstract:

Centrosome asymmetry plays a key role in ensuring the asymmetric division of Drosophila neural stem cells (neuroblasts [NBs]) and male germline stem cells (GSCs) [1-3]. In both cases, one centrosome is anchored close to a specific cortical region during interphase, thus defining the orientation of the spindle during the ensuing mitosis. To test whether asymmetric centrosome behavior is a general feature of stem cells, we have studied female GSCs, which divide asymmetrically, producing another...

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Publication status:
Published

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Publisher copy:
10.1016/j.cub.2007.07.060

Authors


Journal:
Current biology : CB
Volume:
17
Issue:
17
Pages:
1498-1503
Publication date:
2007-09-01
DOI:
EISSN:
1879-0445
ISSN:
0960-9822
Source identifiers:
223389
Language:
English
Keywords:
Pubs id:
pubs:223389
UUID:
uuid:3ed6f90c-a771-4011-99d5-0b2fb65a23f3
Local pid:
pubs:223389
Deposit date:
2012-12-19

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