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Bcl-2 but not FOXP1, is an adverse risk factor in immunochemotherapy-treated non-germinal center diffuse large B-cell lymphomas.

Abstract:

OBJECTIVES: Non-germinal center (non-GC) phenotype, high level expression of the transcription factor forkhead box protein P1 (FOXP1) and anti-apoptotic protein Bcl-2 have been identified as unfavorable prognostic factors for diffuse large B-cell lymphoma (DLBCL) patients treated with chemotherapy. Our aim was to re-evaluate the prognostic impact of these biologic factors on the survival of the patients treated with immunochemotherapy. METHODS: Expression of Bcl-2 and FOXP1, and cell of orig...

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Journal:
European journal of haematology
Volume:
82
Issue:
5
Pages:
364-372
Publication date:
2009-05-05
DOI:
EISSN:
1600-0609
ISSN:
0902-4441
URN:
uuid:3ed2faf6-aa13-4dae-8e3c-81a391f92155
Source identifiers:
246572
Local pid:
pubs:246572

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