Journal article
DNA/long peptide vaccination against conserved regions of SIV induces partial protection against SIVmac251 challenge.
- Abstract:
-
OBJECTIVES: We recently developed a HIVconsv vaccine strategy, consisting of combined conserved regions of HIV-1, to adequately cover viral diversity. To evaluate efficacy in nonhuman primates, an equivalent SIV-derived immunogen SIVconsv was designed and delivered as plasmid DNA or synthetic long peptides. DESIGN: Rhesus macaques lacking protective MHC class I alleles Mamu-A*001 : 01, B*008 : 01, B*017 : 01 were immunized with either SIVconsv synthetic long peptides (S) alone or in combinati...
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- Publication status:
- Published
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- Publisher copy:
- 10.1097/qad.0000000000000047
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Authors
Bibliographic Details
- Journal:
- AIDS (London, England)
- Volume:
- 27
- Issue:
- 18
- Pages:
- 2841-2851
- Publication date:
- 2013-11-05
- DOI:
- EISSN:
-
1473-5571
- ISSN:
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0269-9370
- URN:
-
uuid:3ec6f166-686a-4dab-a0d8-f26e519b916b
- Source identifiers:
-
434355
- Local pid:
- pubs:434355
Item Description
- Language:
- English
- Keywords:
Terms of use
- Copyright date:
- 2013
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