- Abstract:
-
Transcriptional analysis of the human pseudogene psi alpha globin has revealed the following features: (1) The promoter with a 23 bp deletion between the CCAAT and ATA boxes is functional both in vitro and in vivo, 3 fold and 10 fold less efficient, respectively, than alpha. (2) Both the psi alpha and alpha globin gene promoters are active in the absence of transcriptional enhancers, either a gene-encoded or viral enhancer. (3) The mutated poly(A) addition signal in psi alpha (AATGAA) appears...
Expand abstract - Publication status:
- Published
- Publisher copy:
- 10.1093/nar/11.22.7717
-
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- Journal:
- Nucleic acids research
- Volume:
- 11
- Issue:
- 22
- Pages:
- 7717-7733
- Publication date:
- 1983-11-05
- DOI:
- EISSN:
-
1362-4962
- ISSN:
-
0305-1048
- URN:
-
uuid:3ec6e264-1ec1-4817-b595-ae4fe674a7ce
- Source identifiers:
-
22964
- Local pid:
- pubs:22964
- Language:
- English
- Keywords:
- Copyright date:
- 1983
Journal article
Transcriptional activity of the human pseudogene psi alpha globin compared with alpha globin, its functional gene counterpart.
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